The Riordan Intravenous Vitamin C (IVC) Protocol

Vitamin C (ascorbate, ascorbic acid) is a major water-soluble antioxidant that also increases extracellular collagen production and is important for proper immune cell functioning (Hoffman, 1985; Cameron, et al., 1979). It also plays key roles in L-carnitine synthesis, cholesterol metabolism, cytochrome P-450 activity, and neurotransmitter synthesis (Geeraert, 2012). The Riordan intravenous vitamin c (IVC) protocol involves the slow infusion of vitamin C at doses on the order of 0.1 to 1.0 grams ascorbate per kilogram body mass (Riordan, et al., 2003).